Nexera XS inert

Nexera XS inert

Nexera XS inert UHPLC systems achieve a 105 MPa pressure capacity while inhibiting adsorption to metals by using PEEK or ceramic materials in flow channels where samples flow. They also offer excellent resistance to corrosion and a broad range of pH levels, meaning they can be operated reliably using mobile phases that contain high haloid salt concentrations or have extreme pH levels.

For many biopharmaceuticals and medium-molecule drugs, it can be difficult to acquire reliable data using a typical HPLC system, due to adsorption caused by interactions with metal ions. That tendency is particularly true for molecules that contain phosphates, carbonyl groups, or other characteristic elements or functional groups, the adsorption of which can affect analysis in various ways, such as by causing poor peak shape or inadequate sensitivity. Therefore, to increase the sensitivity and accuracy of analysis, it is important to inhibit the adsorption of compounds to the system.

Features

Absorption Inhibited and Detection Sensitivity Improved
Improved Peak Shape and Separation
Assured reliability and Reproducibility
Carry the Day with No Carryover
Quickest Way to results

	Model Name	Features
System controller	SCL-40* CBM-40* CBM-40lite*	Color screen with touch panel and system controller with reservoir tray Number of connectable units : 8 (Using option: 12) , 4(CBM-lite, Excluding built-in solvent delivery unit) Connectable unit : Solvent delivery unit: max. 4, Autosampler: 1, Column oven: max. 4, Detector: max 2, etc.
Solvent Delivery Pump	LC-40D XSi	Pumping method : Parallel-type double plunger (approx. 10 μL/1 stroke) Allowable maximum pressure : 105 MPa Flow rate settings range : 0.0001 to 3.0000 mL/min (1.0 to 105 MPa), 3.0001 to 5.0000 mL/min (1.0 to 80 MPa), 5.0001 to 10.0000 mL/min (1.0 to 22 MPa) Flow rate accuracy :≦± 1% (under specified conditions) Gradient mode : High-pressure gradient (2 or 3 solvents) Quaternary low-pressure gradient
Gradient Mixer	MR Mixer(Inert)	MR 20 µL MR 180 µL MR 40 µL LPGE MR 300 µL LPGE
Degassing Unit	DGU-403* DGU-405*	Number of degassed solvents : 3(DGU-403), 5(DGU-405) Degassed low line capacity : 400 μL/1 line Operating temperature range : 4 to 35°C
Autosampler	SIL-40C XSi	Injection method : Total-volume Injection (standard), loop injection (optional) Allowable maximum pressure : 105 MPa Injection volume : 0.1 to 50 μL, 0.1 to 2000 μL (optional) Injection volume accuracy : ≦± 1% (5 μL injection, n = 20) Injection cycle time : ≦6.7 seconds (under specified conditions)
Column Oven	CTO-40S	Temperature control type : Forced air circulation Cooling Method : Electronic cooling Temperature control range : Room temperature -10 to 85 ℃（CTO-40S） Room temperature -10 to 100 ℃（CTO-40C） Temperature accuracy :±0.8℃（CTO-40S）, ±0.5℃（CTO-40C） Temperature precision : 0.2 ℃（±0.1 ℃、CTO-40S）, 0.1 ℃（±0.05 ℃、CTO-40C）
UV-VIS Detector	SPD-M40* Please contact your local Shimadzu representative.	Light source : Deuterium (D2) lamp Number of diode elements : 1024 Wavelength range : 190 to 700 nm Wavelength accuracy : ≦± 1 nm Wavelength reproducibility : ≦± 0.1 nm
Flow Cell	UHPLC inert cell	Cell volume: 8 μL, Cell path length: 10 mm
	Low-diffusion inert cell	Cell volume: 2.5 μL, Cell path length: 5 mm
	Inert cell	Cell volume: 12 μL, Cell path length: 10 mm
pH monitor	pHM-40	Measurement range：pH 1 to 14 Measurement error：pH ± 0.1 Ambient operating temperature：4 to 35 ℃ Usable humidity range：20 to 85 %
Mobile phase monitor
Software	Labsolutions LC/GC Multi LC-PDA, LabSolutions LCMS Please contact your local Shimadzu representative.

Allowable maximum pressure	105 MPa
Internal rinsing	Standard equipment (3 dil)
Features	Nexera XS inert combines excellent resistance to corrosion with the inertness of surfaces in contact with the sample and mobile phases. The system provides excellent chromatographic separation performances for a wide range of applications.

YOUR WAY OF SUCCESS

Features

Related products

Login